Will there be any issues with changing the account owner? Anything that could break? Anything else to be aware of?
When you change the owner of your Support account, integrations that were set up by the previous account owner may break. For example, if the previous account owner set up the Facebook integration for your Support account, it would have been authorized by the previous owner. The integration fails after the change in ownership because the integration is linked to the account of someone who is no longer the account owner.
You can fix this by having the new account owner re-authorize the integration. For instructions, see: When trying to add my Facebook page it says I am not an Administrator.