Hi Grant Schuemann

Interesting that you are looking for the almost identical problem I tried to solve yesterday.

We actually haven't switched from CCs to CCs and Followers yet. I tried to use the API via a ticket update webhook to remove myself as a CC recipient from tickets I no longer have to be informed about.

The outline of my intended solution is:

- create a trigger which specifies which user to remove from the CC list of the ticket.

- select the respective tickets where I am CC'ed (query: cc:"Peter Hochstrasser")

- add a tag to these tickets, and save them

- the trigger acts on the tag, removed the tag and removes me as a CC using a JSON payload as described here:
https://developer.zendesk.com/documentation/ticketing/managing-tickets/creating-and-updating-tickets/#setting-email-ccs

Much to my dismay, this did not work (besides the fact that there's a typo in the one "action": "delete" example). The webhook executed successfully, but changed nothing. We use the same webhook in other interactions, where it works flawless. Since you use CCs and followers, this may be a way for you, because on the page mentioned above, i.e. here:
https://developer.zendesk.com/documentation/ticketing/managing-tickets/creating-and-updating-tickets/#setting-followers

they talk about followers. I assume that this API works only for CCs and Followers-enabled accounts.
The collaborators API that is available of you're not using CCs and followers only allows to specify the new complete list of collaborators. That cannot be done in a trigger using a webhook, as you need to get and update the contents of the collaborators list.