Asynchronous replies for "create many" jobs

I need to create 1000 tickets and update/patch/create 1000 users. For each, I will need to run 10 jobs since either end point only allows 100 objects per job. Rather than polling the API until the job completes and returns a "completed" status, I would like to run this as asynchronous and get a reply back from the server once it's complete. Is this possible?